The Lariani are in the thick of the race for a Champions League spot after beating Juventus 2-0 and holding Milan to a draw.
Nico Paz returns from suspension, yet is rested ahead of the Coppa Italia semi-final with Inter, but Martin Baturina has an ankle injury, and the season is over for Jayden Addai after a torn Achilles tendon.
Lecce’s run of two consecutive victories was stalled by a 2-0 defeat to Inter, with Kialonda Gaspar, Medon Berisha and Francesco Camarda sidelined. They appear to be going for a 3-5-2 formation, a big change from their usual 4-3-3 or 4-2-3-1.
Como: Butez; Van der Brempt, Ramon, Kempf, Alberto Moreno; Perrone, Da Cunha; Vojvoda, Caqueret, Jesus Rodriguez; Douvikas
Lecce: Falcone; Siebert, Tiago Gabriel, Ndaba; Danilo Veiga, Gandelman, Ramadani, Coulibaly, Gallo; Banda, Cheddira