With Lautaro Martinez and Alessandro Bastoni still out injured, Cristian Chivu turns to Bonny as the strike partner to on-form Thuram.
Yann Bisseck is back in the squad after several weeks out, with Josep Martinez confirmed in goal for the Coppa Italia.
Como have only one injury absentee, as the season is already over for Jayden Addai after tearing his Achilles tendon.
Cesc Fabregas has been keeping teams on their toes with his constantly changing line-up, adopting a three-man defence at times, including this evening.
They had been solid in fourth place in Serie A, but have now managed just one point in three games, the 0-0 with Udinese followed by back-to-back defeats against Inter and Sassuolo.
Nico Paz is allowed a deeper role this time behind Douvikas, with Maximo Perrone pulling the midfield strings alongside Lucas Da Cunha.