Five players will make their senior debuts for Wales when they take on the Barbarians at Allianz Stadium on Saturday (17:00 BST).
Amy Williams and Kelsie Webster are named in the starting backline, while Stella Orrin, Lucy Isaac and Lily Hawkins are among the replacements.
Kayleigh Powell, who shone at full-back during the Six Nations, gets an opportunity at fly-half, with Lleucu George among a host of Premiership Women’s Rugby (PWR) players either rested or unavailable for the uncapped fixture.
Seren Lockwood gets the nod ahead of Keira Bevan at scrum-half, while a fit-again Nel Metcalfe starts at 15.
Metcalfe’s youngster sister Branwen forms part of a strong-looking pack, which features the experience of Sisilia Tuipulotu, Alisha Joyce, Bryonie King and returning captain Alex Callender, along with Wales’ rising star Jorja Aiono.
The game in Twickenham is the second part of a double-header with Wales men facing the Baa-baas at 14:00 BST